Asgard | - At the end of turn four, the player winning Asgard draws two cards from their deck.
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Asteroid M | - Whenever a card is played that costs three energy or four energy, it is moved to Asteroid M.
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Atlantis | - Cards get five additional power while they're at Atlantis, as long as there are no other cards on their side at the same Location.
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Attilan | - At the end of turn three, both players shuffle their hands into their decks and draw three cards.
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Avengers Compound | - Cards cannot be played to any Location other than Avengers Compound during turn five.
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Bar Sinister | - Whenever a card is played to Bar SInister, copies of the card are added to Bar Sinister until it is full.
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Bar With No Name | - The player with the least power at the Bar With No Name wins the location.
- If the Bar With No Name becomes a different location, the player with the most power there wins as normal.
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Baxter Building | - Whichever player is currently winning Baxter Building gets three additional power at the other two Locations.
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Bifrost | - At the end of turn four, every card on the board (not just at Bifrost) moves one Location to the right, if possible.
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Big House | - Cards with a cost of four or higher cannot be played to the Big House.
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Central Park | - Both players get a one-power Squirrel at every location when Central Park is revealed.
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Cloning Vats | - Whenever a card is played to Cloning Vats, a copy of that card is created in its player's hand.
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Counter-Earth | - Whenever a card is played to Counter-Earth, a copy of that card is created at the same Location.
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Crimson Cosmos | - Cards that cost three or less energy cannot be played to Crimson Cosmos.
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Crystal Towers | - When Crystal Towers is revealed, both players shuffle their hands into their decks and draw three cards.
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Daily Bugle | - Each player draws a copy of a random card from their opponent's hand.
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Danger Room | - Whenever a card is played to Danger Room, there is a one-in-four chance that card will be destroyed.
- Cards with On Reveal effects still resolve them before being destroyed.
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Dark Dimension | - Cards played to Dark Dimension are not revealed until after the final turn ends.
- These cards resolve their On Reveal effects, alter power totals accordingly, and then the game ends.
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Death's Domain | - Cards played to Death's Domain are destroyed after they are revealed.
- The cards' On Reveal effects still trigger before they are destroyed.
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Deep Space | - Cards played to Deep Space do not resolve their On Reveal effects.
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District X | - Both players replace their decks with ten cards chosen at random from among all the cards in the game.
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Dream Dimension | - All cards cost one additional energy to play during turn five.
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Ego | - Both players' turns are played automatically by the AI while Ego is revealed.
- If Ego is transformed into another location, players regain control of the game.
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Elysium | - Cards cost one less energy while Elysium is revealed.
- If Elysium becomes a different Location, all card costs immediately return to normal.
- Cards that check another card's cost, such as Elektra, use the original cost rather than the modified one.
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Fisk Tower | - Whenever a card moves to Fisk Tower, that card is destroyed after the movement is resolved.
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Fogwell's Gym | - At the end of the game, both players receive twice the number of Boosters they would normally get.
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Gamma Lab | - At the end of turn three, every card at Gamma Lab becomes a Hulk with twelve power for the rest of the match.
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Genosha | - Cards can be freely moved from other locations to Genosha (but not the other way around)
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Grand Central | - At the end of turn five, a card is automatically played for free to Grand Central from each player's hand, chosen at random.
- No card is played if your hand is empty.
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Hala | - At the end of turn four, all cards at Hala belonging to the player with the least power there are destroyed.
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Hellfire Club | - Cards with a cost of one cannot be played to Hellfire Club.
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Hell's Kitchen | - Both players draw a card with a cost of one from their deck when Hell's Kitchen is revealed.
- If there are no cards in your deck with a cost of one, no card is drawn.
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Ice Box | - One card in each player's hand, chosen at random, has its cost permanently increased by one.
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Isle Of Silence | - Ongoing effects on cards at the Isle Of Silence are nullified.
- A card at the Isle Of Silence can still be affected by an Ongoing effect at a different Location.
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Jotunheim | - Every card at Jotunheim permanently loses one power at the end of each turn.
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Kamar-Taj | - Cards played to Kamar-Taj resolve their On Reveal effects twice.
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Klyntar | - Cards at Klyntar have two less power.
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Knowhere | - Cards do not resolve their On Reveal effects when played to Knowhere.
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Krakoa | - On turn six, both players' cards are played by the AI.
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K'un-Lun | - When a card moves to K'un-Lun, it gains two power.
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Kyln | - No cards can be played to Kyln after turn four.
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Lechuguilla | - Whenever either player plays a card to Lechuguilla, they shuffle three zero-power Rock cards into their deck.
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Lemuria | - Cards played on the turn Lemuria is revealed remain face-down until the end of the following turn.
- Cards do not trigger their On Reveal effects until they are turned face-up.
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Limbo | - The game ends after seven turns, rather than six.
- If Limbo is transformed into another Location before turn seven, the game ends after turn six as normal.
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Los Diablos Base | - At the end of turn three, a random Location is turned into Ruins (see below).
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Luke's Bar | - Whenever a card is played to Luke's Bar, it is immediately returned to its player's hand.
- Cards resolve their On Reveal effects before being returned.
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Machineworld | - Whenever a card is played to Machineworld, the player's opponent gets a copy of that card added to their hand.
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Madripoor | - Cards can be moved freely from Madripoor to other Locations (but not the other way around).
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Mindscape | - At the beginning of turn six, both players swap hands.
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Miniaturized Lab | - Cards cannot be played to Miniaturized Lab on turns three, four, or five.
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Mirror Dimension | - At the beginning of turn four, the Mirror Dimension becomes a copy of one of the other Locations in play, chosen at random.
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Mojoworld | - If one player has more cards than the other at Mojoworld, their total power there is increased by one hundred.
- Neither player gets the bonus if they have an equal number of cards at the Location.
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Monster Island | - Both players get a Monster with nine power at Monster Island when it's revealed.
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Monster Metropolis | - Whichever card has the highest power at Monster Metropolis gets an additional three power.
- If two cards are tied for the highest power, both get the bonus.
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Morag | - The first card played by each player on each turn cannot be played to Morag.
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Mother Mold | - Whenever a card is played to Mother Mold, a Sentinel is created in the player's hand.
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Mount Wundagore | - Whenever a card is played to Mount Wundagore, its player discards a card.
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Muir Island | - At the end of each turn, every card at Muir Island permanently increases its power by one.
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Murderworld | - At the end of turn three, every card at Murderworld is destroyed.
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Necrosha | - Cards at Necrosha have two less power.
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Negative Zone | - Cards at the Negative Zone have three less power.
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New York | - During turn six, both players can move cards to New York from other locations.
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Nidavelir | - Cards have five additional power while they're at Nidavelir.
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Nova Roma | - Both players draw a card from their deck when Nova Roma is revealed.
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Olympia | - Both players draw two cards from their deck when Olympia is revealed.
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Onslaught's Citadel | - Ongoing effects at Onslaught's Citadel are doubled.
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Oscorp Tower | - At the end of turn three, all cards at Oscorp Tower switch sides.
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Pleasant Hill | - Whenever a card is played to Pleasant Hill, its player draws a card.
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Project Pegasus | - Both players get five additional energy the turn Project Pegasus is revealed (and only on that turn).
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Quantum Realm | - Whenever a card is played to Quantum Realm, its power becomes two.
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Ruins | |
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Sakaar | - When Sakaar is revealed, a random card from each player's hand is moved there without paying its cost.
- This does not count as playing the card, and On Reveal effects do not trigger.
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Sanctum Sanctorum | - Cards cannot be played to Sanctum Sanctorum after it is revealed.
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Savage Land | - Both players get a pair of one-power Raptors at Savage Land when it's revealed.
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Sewer System | - Cards at the Sewer System have one less power.
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Shadowland | - Both players get a Ninja at Shadowland that reduces their total power there by two.
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Sinister London | - Whenever a card is played to Sinister London, a copy is added to another location if possible.
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Sokovia | - Both players discard a card at random when Sokovia is revealed.
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Space Throne | - Each player can only have one card at the Space Throne, instead of the usual maximum of four.
- If a player has multiple cards at the Space Throne when it's revealed, they remain there, but more cannot be added until the Location's single slot is empty.
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Stark Tower | - At the end of turn five, each card at Stark Tower gets two additional power for the rest of the match.
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Starlight Citadel | - At the end of turn four, all three Locations change positions.
- Cards played to each Location do not go with them, remaining in their current position and whichever Location ends up there.
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Strange Academy | - At the end of turn five, every card at Strange Academy is moved to one of the other two Locations at random.
- Each card's destination is chosen separately.
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Subterranea | - Both players shuffle five Rocks with zero power into their decks.
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T.A.H.I.T.I. | - Whenever a card is destroyed or discarded, a copy is created at T.A.H.I.T.I.
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The Hub | - Both players get a card added to their hand, each randomly selected from among all the cards in the game.
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The Nexus | - Each player's power at The Nexus is added to their power at the other two locations as well.
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The Peak | - Every card in both players' hands at the time The Peak is revealed switches its power and cost values.
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The Raft | - The first player to have four cards at The Raft draws a card that costs six energy from their deck, and changes that card's cost to zero.
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The Superflow | - Players get one additional energy at the start of each turn if they have no cards at The Superflow.
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The Vault | - Cards cannot be played to The Vault on turn six.
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Tinkerer's Workshop | - Both players get one additional energy the turn Tinkerer's Workshop is revealed.
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Titan | - Cards that cost six energy cost five instead.
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Transia | - When Transia is revealed, all three Locations immediately change positions.
- Cards played to each Location do not go with them, remaining in their current position and whichever Location ends up there.
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Triskelion | - Random cards, chosen from among all the cards in the game, are added to each players' hand until they are full.
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TVA (Time Variance Authority) | - The match ends after four turns instead of six.
- If the TVA becomes a different Location before turn four, the game length returns to normal.
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Utopia | - During turn four, cards at Utopia can move to other locations.
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Vormir | - Players with no cards at Vormir can only play cards to Vormir.
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Wakanda | - Cards at Wakanda cannot be destroyed.
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Wakandan Embassy | - Every card in both players' hands at the time Wakandan Embassy is revealed gets two additional power for the rest of the match
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Warrior Falls | - At the end of each turn, a card in each player's hand is chosen at random. The chosen card permanently increases its power by one.
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Washington, D.C. | - Cards with no abilities get three additional power while in Washington, D.C.
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Weirdworld | - As long as Weirdworld is revealed, players draw from their opponent's deck instead of their own.
- Players draw from their own decks again as normal if Weirdworld becomes a different Location.
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Westview | - At the beginning of turn four, Westview becomes a different Location, chosen at random from all the Locations in the game.
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Worldship | - When Worldship is revealed, both of the other Locations become Ruins.
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Xandar | - All cards get one additional power as long as they're at Xandar.
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X-Mansion | - At the end of turn three, both players get a random card, chosen from among every card in the game, at the X-Mansion.
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